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  • A45 Workstation at the University of Aberdeen
    History Products Services Overseas Distributors Exhibitions Equipment Rental Example Join the Team Workstation Poster Grant Corporate Literature Practical and Clinical Microbiology of Anaerobes Leeds University Microbiology Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific A45 Workstation at the University of Aberdeen Back to Testimonials Date 2013 10 21 Dr Ken Forbes School of Medicine and Dentistry University of Aberdeen purchased a Whitley A45 Anaerobic Workstation in December 2011 The main focus of the research group headed by Dr Forbes is population genetics of human bacterial pathogens There are two broad aims the study of the origins evolution and diversity of specific bacterial pathogens at the molecular level and improving the control of these pathogens through the application of molecular and epidemiological tools Recently studies have focused on Mycobacterium tuberculosis Escherichia coli O157 Listeria species and Campylobacter The A45 Workstation is primarily used for isolating Campylobacter from environmental and food samples by direct plating and by enrichment The workstation is very easy to use and has only required an adjustment to one of the port closures to date Campylobacter grows well in the cabinet with an anaerobic mix 5 Oxygen 10 Carbon dioxide and the balance made up with Nitrogen and the chamber has the capacity to accommodate the large number of plates required for our work The colour touchscreen display is user friendly and allows us to easily monitor relative humidity levels within the cabinet The laboratory has a service and maintenance contract with Don Whitley Scientific and therefore the workstation is serviced annually this provides assurance that the workstation continues to perform correctly with minimal disruption to the processing of large numbers of samples necessary for the research projects The service engineer Mr Bob Cain is always

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/a45-workstation-at-the-university-of-aberdeen/ (2016-02-11)
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  • Hypoxystation for heart research
    Jar System General Laboratory Products Consumables Accessories Service Accreditation Service Accreditation UKAS Calibration Validation Contract Laboratory About Us About Us Certificates Testimonials Export Sales History Products Services Overseas Distributors Exhibitions Equipment Rental Example Join the Team Workstation Poster Grant Corporate Literature Practical and Clinical Microbiology of Anaerobes Leeds University Microbiology Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific Hypoxystation for heart research Back to Testimonials Date 2013 07 30 Three months ago Dr Louise Dunn at The Victor Chang Cardiac Research Institute Darlinghurst NSW received her new Whitley H35 Hypoxystation Dr Dunn and the team in Professor Stocker s Vascular Biology Group are using the Hypoxystation to better understand metabolic reprogramming in ischemia mediated neovascularization how cells change their metabolism to form new blood vessels in low oxygen environments With precise control of oxygen carbon dioxide temperature and humidity Louise says that conducting studies using the Hypoxystation she gets very accurate and reproducible results In Australia more than 10 000 people die from heart failure every year It remains the most common cause of hospital admissions for people aged over 65 however it can affect anyone regardless of age or gender Today The Victor Chang Cardiac Research Institute has 13 laboratories across five research divisions working with a single vision to reduce the incidence severity and impact of heart diseases While their research covers all forms of heart disease the focus is on those that affect the heart s muscle tissue These are the diseases that directly affect the heart s ability to pump enough blood for the body s needs and can cause arrhythmias that in their severest form can lead to sudden death According to Dr Dunn she had the perfect level of help and advice

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/hypoxystation-for-heart-research/ (2016-02-11)
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  • Whitley A35s at Northern General Hospital
    Anaerobic Workstations Whitley Hypoxic Workstations Whitley HEPA Workstations Whitley Instrument Workstations Whitley Microaerophilic Workstations Spiral Plating Lab Automation Tissue Culture Systems Rapid Methods Sample Preparation Media Preparation Colony Counting Autoclaving Environmental Monitoring Anaerobic Jar System General Laboratory Products Consumables Accessories Service Accreditation Service Accreditation UKAS Calibration Validation Contract Laboratory About Us About Us Certificates Testimonials Export Sales History Products Services Overseas Distributors Exhibitions Equipment Rental Example Join the Team Workstation Poster Grant Corporate Literature Practical and Clinical Microbiology of Anaerobes Leeds University Microbiology Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific Whitley A35s at Northern General Hospital Back to Testimonials Date 2013 05 13 Sheffield Teaching Hospitals Foundation Trust recently purchased two Whitley A35 Anaerobic Workstations The major advantage of the A35 Workstation with instant access porthole system is that the movement of plates in and out of the cabinet is much more efficient and can be performed in smaller batches This promotes good practice in placing primary cultures in the correct atmosphere in a quicker timescale There is also the added benefit of being able to read cultures whilst they remain inside the cabinet if so desired At Northern General Hospital in Sheffield we have been using Whitley Workstations for over 30 years I have to say that as well as being one of the reasons we we were confident in purchasing our latest workstations from Don Whitley Scientific is that the maintenance and call out service provided is exemplary In fact all staff members that I have come into contact with whether in person or on the phone have been a credit to the company Steve Davies MA CSci FIBMS Bacteriology Departmental Manager Sheffield Teaching Hospitals Foundation Trust Products Whitley Anaerobic Workstations Whitley Hypoxic Workstations Whitley

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/whitley-a35s-at-northern-general-hospital/ (2016-02-11)
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  • A35 at New Cross Hospital
    University Microbiology Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific A35 at New Cross Hospital Back to Testimonials Date 2013 02 21 At New Cross Hospital we culture all manner of samples from the human body eg blood wound ear nose throat eye and genital swabs pus tissues sputum urines and faeces In addition we have a serology and molecular section We process approximately 370 000 samples per annum We use the Whitley A35 Workstation for the culture of anaerobes from blood culture ear wound tissue and pus samples It is used regularly by around 16 members of staff The key features to us of the A35 are It uses less gas due to a smaller airlock smaller than the old Whitley Workstation we had We can also use nitrogen in addition to the anaerobic gas mixture and this is therefore cheaper We have the sleeveless option which is easier and uses less gas We have the ability to put in single plates through the letterbox There is plenty of room within the cabinet and it is well lit We have the removable front version which means we are able to take the front off completely if required for cleaning purposes We also find the touch screen easy to use The A35 complements other anaerobic work equipment in our laboratory as the other anaerobic work we do in terms of identification and sensitivity testing is based on anything we isolate from this system This workstation has helped improve workflow and working practices procedures particularly as the airlock cycle is completed rapidly so no time is wasted trying to change gloves etc Being able to use the letterbox on call and for single plates is also less time consuming

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/a35-at-new-cross-hospital/ (2016-02-11)
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  • Whitley 1000 Workstation
    Workstation Poster Grant Corporate Literature Practical and Clinical Microbiology of Anaerobes Leeds University Microbiology Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific Whitley 1000 Workstation Back to Testimonials Date 2012 10 04 Dr Steve Cartman is a Senior Research Fellow at the University of Nottingham and has been using a Whitley 1000 Workstation for the last ten years He is a member of the Clostridia Research Group which was established by Professor Nigel Minton in 2004 Today the laboratory at Nottingham has eight DWS workstations in one laboratory Professor Minton s laboratory which developed the ClosTron a universal system for gene knock out in Clostridium species currently has two major avenues of research on going 1 Clostridium difficile This hospital superbug causes a potentially fatal diarrhoeal disease and is the major cause of hospital acquired infection in Europe and North America Their research is aimed at gaining a better understanding of the infection process with a view to developing more effective countermeasures 2 Biotechnology Biological engineering This area of research harnesses industrially valuable properties of bacteria with a view to producing chemicals and second generation biofuels Don Whitley workstations are vital to their research programmes because the microorganisms they work with are obligate anaerobes They have several users per workstation meaning that workstations are in constant use with little respite The reliability and robust nature of the workstations means that their research programmes can progress without interruptions due to equipment failure All their workstations are on a Don Whitley Scientific service contract Steve rates their particular service engineer as outstanding Regular servicing is taken care of without staff having to remember that a service is due and go to the trouble of having to call in to book

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/whitley-1000-workstation/ (2016-02-11)
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  • H35 Hypoxystation-3
    Prize Posters Refurbished Equipment Secure Login Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific H35 Hypoxystation 3 Back to Testimonials Date 2012 08 17 Accurate control of the oxygen tension to which cells are exposed to has become an important consideration in many aspects of biomedical research At King s College London our customers Giovanni Mann Professor of Vascular Physiology at Kings College London and Richard Siow Senior Lecturer in Physiology are investigating how altering levels of oxygen regulate the function of cardiovascular cells Professor Mann s team is part of the British Heart Foundation Centre of Research Excellence at King s College London His research focuses on vascular dysfunction induced by oxidative stress in diseases such as atherosclerosis pre eclampsia and diabetes Until recently Professor Mann s team used a CO 2 incubator which enabled them to reduce the level of oxygen but did not provide an accurate control to achieve well defined oxygen environments for long term cell culture studies It was also necessary to remove the cells from the incubator in order to work with them exposing them periodically to higher levels of oxygen Through a research and development collaboration between Professor Mann and Dr Siow with Don Whitley Scientific their group now uses a workstation to conduct experiments in vascular cells under well defined oxygen environments providing results that would have been very difficult to obtain in a standard CO 2 incubator According to Professor Mann The Whitley Workstation has provided us with a system that allows us to control oxygen concentrations accurately We can manipulate cells under low oxygen conditions and continue to conduct experiments under well defined environmental conditions The design of this workstation has also allowed us to use other essential equipment inside the chamber such as

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/h35-hypoxystation-3/ (2016-02-11)
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  • H35 Hypoxystation-2
    Contact Us 44 0 1274 595728 sales dwscientific co uk Follow Don Whitley Scientific H35 Hypoxystation 2 Back to Testimonials Date 2012 08 01 One of our Whitley H35 Hypoxystation customers comments on his use of the workstation and explains how it is helping in his research The cellular response to low oxygen is a central component of a number of diseases including cancer diabetes and cardiovascular disease We are interested in the signalling processes behind oxygen sensing and in particular how changes in oxygen tension are reflected in the metabolic phenotype of a cell We use the Whitley H35 Hypoxystation to provide a well controlled hypoxic environment in which to culture mammalian cells over short time periods 30 minutes to 4 days mainly using 1 and 0 1 oxygen tensions We also use it to produce hypoxia reoxygenation cycles to recapitulate some specific disease phenotypes We have had the system in the laboratory here for 6 months although I have previously used another H35 for 18 months and before that used a different make of hypoxia workstation for 6 years In my laboratory four people use it and it is in service almost 24 7 The key features of the Hypoxystation are the ability to control both oxygen and CO 2 levels as well as being able to set a programme to cycle between different oxygen tensions multiple times overnight It goes without saying that as with all mammalian tissue culture we also need to have excellent temperature control and humidity for all of our experiments In addition in our experience the H35 uses less nitrogen than other similar instruments reducing the cost of experiments The precise control of oxygen tension by the H35 has improved the quality of our results considerably Also a previous instrument I used did

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/h35-hypoxystation-2/ (2016-02-11)
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  • H35 Hypoxystation-1
    proposed that hypoxia had a role in the pathogenesis and progression of cancer Since this pioneering work the role of hypoxia in cancer has broadened significantly and is now appreciated to affect every major aspect of cancer biology A unique environment The low oxygen tumour environment is one of acidic pH low nutrients and high catabolites and contains cells with characteristics different to those of normal cells Tumour hypoxia has shown to be a prognostic marker of disease progression and can influence the outcome of chemotherapy and radiotherapy Targeting hypoxic cells using conventional therapies has proved difficult However as this environment is one unique to solid tumours it is a potential target for therapeutic intervention using drugs designed to act selectively on these cells The latest research has focused on understanding the biology of hypoxic tumour areas and developing anti cancer drugs that are effective in low oxygen environments Creating the right atmosphere When carrying out any type of cell research scientists aim to recreate in the laboratory in vitro the same conditions as found in the body in vivo Precise measurement and control of oxygen tension are critically important in biological tumour models Most hypoxia research is carried out at below 5 and typically between 0 2 and 0 5 Technology that can provide accurate control and measurement of gas concentrations is essential in order to study tumour mechanisms and perform candidate drug testing under relevant and reproducible conditions The importance of replicating in vivo oxygen levels in vitro has also been proposed beyond cancer research Currently most cell biology research is done in an environment with normal atmospheric oxygen levels of around 21 The cells of our body are used to much less than this usually in the range of 10 down to 0 5 When cells are cultured they are usually kept in an incubator with 0 2 oxygen However when removed for manipulation they are exposed to atmospheric oxygen levels Chandan and colleagues proposed that exposing cells to an unnaturally rich oxygen environment triggers cellular stress and significant physiological changes In order to maintain truly representative physiological conditions workstations offering tight control of gas levels temperature and humidity are recommended for cell research Targeting tumour cells Dr Roger Phillips at the University of Bradford s Institute of Cancer Therapeutics researches tumour hypoxia and the biological and therapeutic aspects associated with it Dr Phillips team use a specialised workstation Hypoxystation Don Whitley Scientific to replicate the tumour environment They carry out cellular assays to investigate the anti cancer effects of different compounds over a closely controlled range of oxygen tensions Specifically they are researching drugs which are designed to be activated under hypoxic conditions These are pro drugs inactive compounds which are metabolised to become cytotoxic Designed in conjunction with Dr Phillips himself the modified atmosphere workstation can be used for cell biology research requiring normoxic hypoxic and anoxic conditions It offers precise control of oxygen and carbon dioxide as well as temperature and relative humidity With

    Original URL path: http://www.dwscientific.co.uk/about-us/testimonials/h35-hypoxystation-1/ (2016-02-11)
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web-archive-uk.com, 2017-12-17