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  • July 2015 | Don Whitley Scientific Archive -
    of bone morphogenetic protein BMP2 expression modulation of chemokine C X C motif receptor CXCR2 signaling and LEPR upregulation as causative factors for enhanced hMSC isolation at hypoxia The term extraphysiologic oxygen shock stress EPHOSS for hematopoietic stem cells experiencing hyperoxia outside of their natural niches is introduced by Mantel et al from Indiana University They delineated the detrimental effects of even brief exposure of bone marrow and cord blood to ambient conditions as compared to harvesting and processing HSC s at constant 3 hypoxia Up to 5 fold increased cell numbers and improved engraftment of transplanted HSC s as a result of hypoxic conditions led the authors to question the relevance of the work currently being carried out at ambient oxygen They attribute the beneficial effects of low oxygen on the yield and function of BM and CB stem cells to reduced production of reactive oxygen species ROS implicating the mitochondrial permeability transition pore MPTP cyclophilin CypD and p53 in protection from EPHOSS Mantel et al predict that hypoxic processing will be significant for many other cell types and phenomena such as metabolism of cancer cells and stem cell aging This article was written by Burga Kalz Fuller Product Manager at HypOxygen Alun Kitsell Burga Kalz Fuller and Daniel Secker with a Whitley HI35 Hypoxystation Kay et al BMP2 repression and optimized culture conditions promote human bone marrow derived mesenchymal stem cell isolation 2015 Med 10 2 109 125 Mantel et al Enhancing hematopoietic stem cell transplantation efficacy by mitigating oxygen shock 2015 Cell 161 1553 1565 Tweet A guide to Don Whitley Scientific at IBMS 2015 Posted on July 14th 2015 by Alex Rhodes Categories Australia Exhibitions Germany News Press Releases No Comments Tags Don Whitley Scientific IBMS IBMS Congress 2015 Institute of Biomedical Science The IBMS Congress is the Institute of Biomedical Science s bi annual event providing three full days of active learning in science education training management and leadership held at Birmingham s ICC on the 28 30 September Don Whitley Scientific will once again be exhibiting its range of innovate scientific equipment and invites attendees to come and see the instruments we manufacture and learn about the solutions and service we can provide As well as lectures and exhibitions IBMS will continue to have a schedule of lively social events to encourage networking and to enhance the enjoyment of the IBMS experience To keep up to date with IBMS Congress 2015 use ibmscongress15 or follow BiomedScience on twitter alternatively keep checking the Don Whitley Scientific blog and social network profiles to find out more about our involvement at one of the largest biomedical science events in Europe Don Whitley Scientific can be found at stand 220 in Hall 4 of the Exhibition Admittance to the exhibition is free and the options to register can be found at https www ibms org congress go exhibition Tweet Whitley Colour Touchscreens Posted on July 10th 2015 by Alex Rhodes Categories Anaerobic Australia Germany Hypoxystations News Press Releases

    Original URL path: http://www.dwscientific.co.uk/blog/2015/07/ (2016-02-11)
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  • June 2015 | Don Whitley Scientific Archive -
    sowie die Krebsforschung Das ist ein weiterer Meilenstein in der Entwicklung des Gewerbegebiets Ost Und für Herzlake ein großer Schritt nach vorn sagte Gemeindebürgermeister Hans Bösken beim ersten Spatenstich und wünschte dem Unternehmen viel Erfolg Dem schloss sich Samtgemeindebürgermeister Ludwig Pleus an Aus Lähdener Sicht sehe man den Umzug zwar mit einem weinenden Auge doch immerhin bleibe die Firma in der Samtgemeinde Hier sind Sie gut aufgehoben so Pleus Neuer Sitz für Laborgerätevertrieb Meintrup DWS zieht von Holte Lastrup nach Herzlake noz de Lesen Sie mehr auf http www noz de lokales herzlake artikel 589024 meintrup dws zieht von holte lastrup nach herzlake Tweet Stem Cell Research in Stockholm Posted on June 25th 2015 by Deborah Robinson Categories Australia Exhibitions Germany Hypoxystations News Press Releases No Comments Tags Cell Culture Workstation H35 Hypoxystation hypoxia workstation hypoxic workstation Hypoxystation Stem Cell Workstation Stem cell researchers from all over the world are currently convening in Stockholm for the annual meeting of the International Society for Stem Cell Research ISSCR Topics covered in the event range from pluripotency and differentiation through regeneration to disease modelling and tissue engineering All aspects of reprogramming and stem cell maintenance on the one hand and differentiation on the other hand are intricately influenced by the cellular microenvironment Oxygenation is a crucial parameter throughout all these processes both in the natural stem cell niche and during culture in the lab Low oxygen promotes efficient expansion of stem cells in culture while supporting maintenance of the stem cell phenotype Hypoxia can increase the proliferation rate and inhibit senescence of stem cells and promote healing directly and through paracrine effects Therapies utilizing hypoxic cells exhibit improved homing and engraftment to the target tissues as compared to normoxia Hypoxia is a major determinant of many diverse aspects of stem cell biology Don Whitley Scientific will be at the event exhibiting their largest cell culture workstation to date the Whitley H135 Hypoxystation Tweet Meintrup DWS nächstes aW Seminar Posted on June 23rd 2015 by Deborah Robinson Categories Germany No Comments Seit langem ist die Wichtigkeit der Überprüfung des freien Wassers der Industrie bekannt Die Messungen der sogenannten Wasseraktivität aW bildet dazu die Grundlage und liefert wichtige Informationen über die Qualität eines Produktes Sie gibt Auskunft über das mikrobiologische Wachstum auf der Oberfläche Somit können zuverlässige Aussagen über Stabilität und Haltbarkeit einer Probe gemacht werden Am 02 09 2015 findet unser 3 aW Seminar in Hamburg statt Dies richtet sich an alle Interessierten im Bereich aW Messtechnik Ob Sie die Wasseraktivät aW schon messen oder nicht spielt keine Rolle Erfahrungen können ausgetauscht werden Außerdem hören Sie Vorträge von Spezialisten und haben die Möglichkeit Ihre eigenen Proben mitzubringen um die Wasseraktivität zu bestimmen Im Anschluss entführen wir Sie in die Welt der Schokolade Kosten für dieses Seminar 195 00 zzgl MwSt Klicken Sie hier für unser Anmeldeformular www meintrup dws de assets product pdfs aw aW Seminar pdf Tweet 73 Jahreskongress der SGM Posted on June 22nd 2015 by Deborah Robinson Categories Anaerobic Germany

    Original URL path: http://www.dwscientific.co.uk/blog/2015/06/ (2016-02-11)
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  • May 2015 | Don Whitley Scientific Archive -
    a reliable and efficient media preparator With the ability to produce anywhere between 9 and 60 litres of agar broth fluid media we offer a range of Masterclaves to suit every laboratory See the table below for a feature comparison Masterclave 09 Masterclave 528 Masterclave 60 Media preparation capacity 1 9 L 5 28 L 10 60L Sterilisation temperature 95 125 C 95 125 C 95 125 C Can be linked to plate pouring devices and gravimetric diluters Eliminates risks associated with manual preparation of media in glass vessels Integral ticket printer Optional chart recorder Transport wheels optional trolley Range of safety features including automatic locking L R Masterclave 09 528 60 The combination of a Masterclave and an automated pourer stacker provides the ideal media production system giving maximum flexibility to produce the amount you need when you need it whilst also minimising the risk of contamination and repetitive strain injury If quantity demands are high and workspace restricted the APS One Pourer Stacker could be exactly what you are looking for The most compact automated Petri dish filling and distribution system on the market this machine is able to process 800 plates 18ml per hour It is also the only plate pourer that rotates the Petri dish as it dispenses the media thereby providing a level agar surface Read more Tweet H135 at Keystone Symposia Dublin Posted on May 13th 2015 by Deborah Robinson Categories Australia Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases No Comments Tags Exhibitions H135 Hypoxic Workstation Keystone Symposia Whitley i2 Instrument Workstation Representatives from Don Whitley Scientific and our American distributor HypOxygen are attending the Keystone Symposia on Hypoxia From Basic Mechanisms to Therapeutics this week in Dublin Ireland From May 12th 17th you will have the opportunity to see the brand new Whitley H135 HEPA Hypoxic Workstation Delegates attending the Keystone Meeting can pick up a free Hypoxia t shirt from the DWS stand while stocks last The largest workstation in our range the H135 pictured left has an enormous capacity for working and incubation of over 550 litres Combined with the ability to house large pieces of equipment such as live cell imaging devices microscopes plate readers and more it s our most revolutionary Hypoxystation yet Without compromising on quality or precision this innovative product allows you to take your research to new heights whilst maintaining confidence in your results Some of the great features include Rapid 12L airlock 3 gas operation Automated O 2 calibration Removable front Option for Whitley Internal HEPA Filtration System with Enhanced Biological Containment Read more Tweet Cell Press Webinar Available On Demand Posted on May 8th 2015 by Deborah Robinson Categories Australia Exhibitions Germany Hypoxystations News Press Releases No Comments Tags Cell Press H35 H35 Hypoxystation In last month s Cell Press webinar Dr Randall Johnson of the University Cambridge and Dr Hannele Ruohola Baker of the University of Washington spoke about the role of the hypoxic microenvironment in physiological contexts as diverse as cancer

    Original URL path: http://www.dwscientific.co.uk/blog/2015/05/ (2016-02-11)
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  • April 2015 | Don Whitley Scientific Archive -
    primary cause has been identified as the spirochaetal bacteria treponemes A comprehensive bacterial molecular survey of sheep contagious ovine digital dermatitis CODD lesions has not been done to determine if there is a shared etiopathogenesis between BDD and CODD Also there have been only anecdotal reports of BDD lesions occurring in beef cattle with no definitive published data on the disease Additionally little is known about the transmission of Treponema bacteria It may be possible that DD treponemes are carried in both cattle and sheep gastrointestinal GI tracts and then shed in faeces and spread Another route of transmission may be via farm equipment This study investigated ruminant GI tissues and farm equipment for the presence of DD treponemes Additionally sheep and beef DD lesions were analysed for the presence of DD treponemes by PCR and culture techniques The full poster can be viewed here Tweet HypOxygen at AACR Meeting Posted on April 20th 2015 by Deborah Robinson Categories Exhibitions Hypoxystations News Overseas Exhibitions Press Releases No Comments Tags AACR H35 HEPA H35 Hypoxystation i2 Workstation Whitley i2 Instrument Workstation Our American distributors HypOxygen are exhibiting Whitley Workstations at this year s AACR meeting in Philadelphia Go over to their stand to see the i2 Instrument Workstation specifically designed to house a Seahorse XF Analyzer in physiologically relevant conditions H35 Hypoxystation and also to learn about our range of HEPA workstations Pictured here is Evan Kitsell Design Director at Don Whitley Scientific Ltd and Dr Burga Kalz Fuller Product Manager at HypOxygen They will be available to demonstrate the workstations and answer any questions you may have As the AACR s website describes this year s meeting will highlight the latest most exciting discoveries in every area of cancer research and will provide a unique opportunity for investigators from all over the world to meet interact and share their insights This year s meeting theme Bringing Cancer Discoveries to Patients underscores the vital and inextricable link between discovery and treatment and it reinforces the fact that research underpins all the progress we are making in the field toward cancer cures Tweet Cell Press Webinar Hypoxic Microenvironments Posted on April 13th 2015 by Deborah Robinson Categories Hypoxystations News Overseas Exhibitions Press Releases No Comments Tags Cell Press hypoxia HypOxygen Hypoxystation The hypoxic microenvironment triggers many of the events underlying cancer progression and stem cell maintenance and or differentiation In maintaining oxygen homeostasis oxygen levels are sensed by mitochondria communicated by reactive oxygen species ROS and conveyed by hypoxia inducible factors HIF s Hypoxia signalling pathways have far reaching consequences for cellular and tissue processes from metabolism through angiogenesis to metastasis Dr Hannele Ruohola Baker University of Washington and Dr Randall Johnson University of Cambridge will be speaking at the upcoming Cell Press webinar on Hypoxic Microenvironments which Don Whitley Scientific and HypOxygen are proud to sponsor Dr Ruohola Baker s lab investigates metabolic determinants of and miRNA function in stem cells and Dr Johnson examines the effects of hypoxia in cancer

    Original URL path: http://www.dwscientific.co.uk/blog/2015/04/ (2016-02-11)
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  • March 2015 | Don Whitley Scientific Archive -
    Releases No Comments Tags A95 Anaerobic Cabinet Anaerobic Conditions Monitor The Whitley A95TG three gas Anaerobic Workstation is currently the largest model in our range with a maximum capacity of between 1000 and 1400 x 90mm Petri dishes It is also extremely cost effective with an operating cost saving of 30 compared to the dual gas option The large integral 30 litre airlock with automatic internal door is 20 faster than our previous MG1000 model with the cycle taking just 5 minutes Each porthole also acts as a mini airlock so you can transfer 10 plates through each time you enter or exit the workstation thereby reducing unnecessary airlock cycles when processing small sample quantities Ideal for use in teaching hospitals and university laboratories the four access ports allow two users to work side by side Available with fully integrated Anaerobic Conditions Monitor with data download facility other options include internal power sockets bespoke trolley and single plate entry systems For more details please contact us Tweet H35 HEPA Testimonial Video Posted on March 23rd 2015 by Deborah Robinson Categories Hypoxystations News Press Releases No Comments Tags H35 Hypoxystation HEPA Hypoxystation HEPA Workstation Testimonials In this video Dr Michael Cross from the MRC Centre for Drug Safety Science University of Liverpool discusses his current research involving the incubation of cardiac spheroids Dr Cross uses a Whitley H35 HEPA Hypoxystation and explains the benefit of the HEPA filtration system in providing a sterile environment for the prolonged culture of cells in physiologically relevant conditions For more information about Don Whitley Scientific s unique HEPA filter click here Tweet 2 Day Anaerobe Course Posted on March 16th 2015 by Deborah Robinson Categories Anaerobic News Press Releases No Comments Tags Anaerobic Microbiology Anaerobic Workstation Clinical Microbiology Guide Identifying Clinical Anaerobes The Society for Anaerobic Microbiology is presenting a 2 day residential course sponsored by Don Whitley Scientific and delivered by The UK Anaerobe Reference Unit Public Health Wales Cardiff 25 26 June 2015 Is it time to refresh your knowledge on the culturing identification and clinical importance of anaerobes Are your staff wanting to learn from experts about the latest technologies and techniques Book now ONLY 1 PLACE REMAINING as of 29 04 15 Cost 350 VAT 330 VAT for SAM members which includes One night accommodation at the Park Plaza Hotel Cardiff and all meals and refreshments plus dinner on 25th June IBMS RCPath CPD accreditation applied for Invaluable preparation for FRCPath Aims of the course 1 To promote an understanding and awareness of anaerobic bacteria in clinical material 2 To gain an insight into their relevance in clinical microbiology 3 To achieve a basic level of competence in methods used for their isolation and identification 4 To improve the standards of anaerobic microbiology in clinical laboratories Speakers include Trefor Morris Lead Scientist UKARU Dr Sheila Patrick Chair Society for Anaerobic Microbiology For more information and a detailed programme please visit the Don Whitley Scientific website www dwscientific co uk practicalmicrobiologycourse To

    Original URL path: http://www.dwscientific.co.uk/blog/2015/03/ (2016-02-11)
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  • February 2015 | Don Whitley Scientific Archive -
    of response to set point changes as those achievable in Whitley Hypoxystations Read more Tweet The Science Behind Three person Babies Posted on February 10th 2015 by Deborah Robinson Categories Australia Germany Hypoxystations News Press Releases No Comments Tags hypoxia hypoxic workstation IVF Last week the House of Commons voted to allow in vitro fertilisation IVF to be carried out with eggs from two different women and sperm from one man a technique which has been dubbed the three person baby The vote opened a novel avenue for treating mitochondrial diseases because the actual nuclear mother whose family would have a history of mitochondrial MT diseases does not pass on her mitochondria with the baby receiving the female donor s healthy mitochondria instead Dr Burga Kalz Fuller product manager at HypOxygen presents an interesting outline of the scientific implications and explains why the media s term three person baby is a misnomer Read more Tweet Culturing Tissue Engineered Constructs of Clinically Relevant Size Using Perfusion Posted on February 9th 2015 by Deborah Robinson Categories Australia Germany Hypoxystations News No Comments Tags culture chambers Culture under perfusion culturing tissue flow conditions TC 3 Bioreactor tissue engineering What is in vitro tissue engineering In vitro tissue engineering is a relatively recent phenomenon that usually refers to cell culture systems combining biomaterials tissue specific cells and chemicals such as growth factors and cytokines that aim to direct the behaviour of the cells in the way they interact with their material scaffolds and each other These tissue engineered constructs may then be used in a variety of model systems or they may be cultured with the aim of creating a suitable transplant Why is it useful The advantages of a tissue engineered transplant graft are numerous patient tailored design lack of donor site morbidity and the opportunity to use autologous cells in order to avoid the host immune response to name just a few The advantages of tissue engineered model systems are similarly numerous with the most significant probably being the reduction in the research community s reliance on animal models and improved safety when animal trials are used Read more Tweet Studying Mitochondria in Hypoxia Posted on February 4th 2015 by Deborah Robinson Categories Australia Germany Hypoxystations News Overseas Exhibitions Press Releases No Comments Tags hypoxia workstation Hypoxystation Whitley i2 Instrument Workstation Having recently attended the joint symposium on Mitochondria Metabolism and Heart Failure and Diabetes and Metabolic Dysfunction in Santa Fe New Mexico our product manager Dr Burga Kalz Fuller of HypOxygen was fascinated by the enthusiasm of the attendees and the wide range of topics Some of these included Metabolic communication between different organs and tissues based on energy expenditure Anti diabetic and anti obesity effects of thermogenic pathways in brown and beige fat PINK1 and Parkin in mitophagy and MAPL Drp1 in mitochondrial fission The role of mitochondrial DNA in ageing and degenerative diseases The influence of gut microbiota on human metabolism and gene expression through accessing intestinal chromatin Localisation

    Original URL path: http://www.dwscientific.co.uk/blog/2015/02/ (2016-02-11)
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  • January 2015 | Don Whitley Scientific Archive -
    bacteria Read more Tweet Did You Know Whitley Workstations are Ethernet enabled for Remote Access Posted on January 20th 2015 by Deborah Robinson Categories Australia Germany Hypoxystations News Press Releases No Comments Tags A35 workstation A45 Workstation A55 Workstation A95 Anaerobic Cabinet anaerobic chamber Anaerobic Microbiology Anaerobic Workstation Don Whitley Scientific environmental monitoring H35 Hypoxystation H45 Hypoxystation HEPA Filtration hypoxia workstation hypoxic workstation Hypoxystation temperature monitoring Whitley A85 Workstation Have you ever wanted to check the status of your Whitley Workstation when you were away from the lab Well now you can Most of our new workstations are Ethernet enabled so you can dial in and access the touch screen control panel from the other side of the building or even from the other side of the world This allows you to check the current operating conditions of the workstation and if activated view any of the graphical screens If necessary you can then make changes to the parameters i e temperature humidity O 2 and CO 2 levels from wherever whenever Read more Tweet Workstation Users Could be Entitled to 250 Posted on January 13th 2015 by Deborah Robinson Categories Australia Germany Hypoxystations News Press Releases No Comments Tags anaerobic chamber Anaerobic Microbiology Anaerobic Workstation Clinical Microbiology Guide Don Whitley Scientific hypoxia workstation hypoxic workstation Hypoxystation Do you use a Whitley Workstation You could be entitled to 250 Our travel grant scheme has now been extended to cover the use of any Whitley Workstation or Hypoxystation If you have used a Whitley Workstation and cited its use on your poster or published paper contact us and you could be eligible for a grant of 250 Various grants are available for those mentioning the use of any Whitley Workstation or Hypoxystation in a published paper or a poster they are going to present In return Don Whitley Scientific will ask for a copy of the paper poster so we can promote the featured range to others If we are exhibiting at the event you are presenting your poster at we can provide copies to everyone who visit s our stand if this is something you would like To apply for this grant please send a copy of your poster or paper along with your contact details to Steve Robertson dwscientific co uk If you are presenting a poster don t forget to let us know the title of the event and the date you will be making your presentation Tweet Did You Know The A55 is a Dual Temperature Workstation Posted on January 13th 2015 by Deborah Robinson Categories Australia Germany News Press Releases No Comments Tags A55 Workstation anaerobic chamber Anaerobic Workstation Don Whitley Scientific Whitley A55 Workstation Whilst the Whitley A55 Anaerobic Workstation s large capacity allows two people to work side by side in the same environmental conditions this workstation is unique in our range as it can also be supplied with a central partition to separate the workstation into two chambers This permits the user to

    Original URL path: http://www.dwscientific.co.uk/blog/2015/01/ (2016-02-11)
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  • December 2014 | Don Whitley Scientific Archive -
    from the main chamber When you open the compartment door the plate carrier basket swings outwards to allow easy access It has a capacity of 10 x 90mm Petri dishes or items of a similar size The temperature in the Chilled Incubation Compartment can be easily adjusted in 0 1 C increments via the workstation s colour touchscreen The operating temperature range is between 12 C and 25 C and the temperature distribution within the compartment is within 2 C This option must be specified at time of order as it is a factory fitted modification Laboratory and main chamber temperatures may influence the upper and lower temperature levels that can be achieved Tweet Biological Containment Posted on December 19th 2014 by Deborah Robinson Categories Australia Germany Hypoxystations News No Comments Tags H35 Hypoxystation HEPA Filtration HEPA Workstation hypoxia workstation hypoxic workstation Looking for extra biological containment from your workstation If you need additional biological containment within your HEPA filtered Workstation there is now an option to reduce biological discharge from the chamber via the gas outlets The Whitley Enhanced Biological Containment System involves fitting HEPA filters to the two gas outlets on a Whitley HEPA Workstation Laboratory tests were conducted on an H35 Hypoxystation to deliberately challenge the exhaust filters with high concentrations of aerosolized bacterial cells and quantify their discharge through the exhaust valve filters The results of this experiment demonstrated that the system achieved a substantial reduction in bacterial loading better than 99 999 within the discharged gas A paper detailing the full methodology and results of this study can be found here Tweet New Storage Rack Available Posted on December 17th 2014 by Deborah Robinson Categories Australia Germany Hypoxystations News Press Releases No Comments Tags H35 Hypoxystation HEPA Workstation hypoxia workstation hypoxic workstation storage shelves Hypoxystation hypoxystation storage rack tissue culture flask storage Here s a new storage rack that we have designed for use with our Hypoxystation range Manufactured from aluminium and finished in a durable white powder coating this storage facility is comprised of three shelves and can accommodate up to 6 multi well plates twelve T25 tissue culture flasks or a combination of these and other labware Storing your samples in this manner allows the atmosphere to circulate evenly and thereby optimises the conditions for your cells It is also freezer and incubator safe Contact us for more information and quote product code A03780 Tweet Did You Know about HEPA Filtration Posted on December 12th 2014 by Deborah Robinson Categories Australia Germany Hypoxystations News No Comments Tags A35 workstation Anaerobic Workstation Don Whitley Scientific H35 Hypoxystation H45 Hypoxystation HEPA Filtration HEPA Workstation hypoxic workstation HEPA or High Efficiency Particulate Air is a filtration system which ensures the utmost product protection for your samples Unlike competitor systems that draw atmosphere out of the workstation before filtering and reintroducing it Don Whitley Scientific has created a unique design which is housed completely inside the workstation Housing the HEPA system inside the chamber prevents the build

    Original URL path: http://www.dwscientific.co.uk/blog/2014/12/ (2016-02-11)
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web-archive-uk.com, 2017-12-11