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  • Easy Oxygen Calibration
    and easily and so improve the accuracy of experimental data The Whitley Automated Calibration System patent pending is very user friendly all you have to do is touch a couple of icons on the colour touchscreen and the routine activates No further user intervention is required It takes just eight minutes to complete and readings are taken at two points 0 oxygen and 20 9 oxygen levels You don t have to enter the chamber at all The oxygen sensor is not removed for calibration so the sensor remains within a stable environment and is not subjected to any changes in humidity and temperature when a calibration routine is conducted Leaving the sensor in place prevents the risk of condensation forming on the component which could affect its sensitivity accuracy and life You can set the system to prompt you when the next calibration is due from 7 21 days Don Whitley Scientific recommends that calibration is conducted every two weeks Full training confirming how easy the routine is to perform is provided during the workstation installation procedure Click on the image below for a video demonstration Leave a Reply Click here to cancel reply You must be logged in to post a comment Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014

    Original URL path: http://www.dwscientific.co.uk/blog/easy-o2-calibration/ (2016-02-11)
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  • Tag Archive for "02 Calibration" -
    This system allows you to calibrate your workstation efficiently and easily and so improve the accuracy of experimental data The Whitley Automated Calibration System patent pending is very user friendly all you have to do is touch a couple of icons on the colour touchscreen and the routine activates No further user intervention is required It takes just eight minutes to complete and readings are taken at two points 0 oxygen and 20 9 oxygen levels You don t have to enter the chamber at all The oxygen sensor is not removed for calibration so the sensor remains within a stable environment and is not subjected to any changes in humidity and temperature when a calibration routine is conducted Leaving the sensor in place prevents the risk of condensation forming on the component which could affect its sensitivity accuracy and life You can set the system to prompt you when the next calibration is due from 7 21 days Don Whitley Scientific recommends that calibration is conducted every two weeks Full training confirming how easy the routine is to perform is provided during the workstation installation procedure Click on the image below for a video demonstration Tweet Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014 August 2014 July 2014 June 2014 May

    Original URL path: http://www.dwscientific.co.uk/blog/tag/02-calibration/ (2016-02-11)
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  • Whitley Colour Touchscreens
    Releases No Comments Tags Anaerobic Workstation Colour Touchscreens Don Whitley Scientific hypoxic workstation Tweet Don Whitley A and H Workstations now feature modern easy to use colour touch screen interfaces These colour touchscreens replace the gauges dials and switches of workstations of the past and are a fitting match for the advanced scientific instruments that Don Whitley Scientific provide All options and settings you would expect to access on your Don Whitley workstation feature on these unique clear displays Set password protected user levels to control what can be done and by whom on the workstation Complete a range of functions such as O2 calibration and humidity Control mains power internal lights and set audible alarms A generous screen size of 7 making controlled parameters easily visible Download temperature humidity and chamber pressure data in seconds via USB Unique to Don Whitley workstations Leave a Reply Click here to cancel reply You must be logged in to post a comment Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014 August 2014 July 2014 June 2014 May 2014 April 2014 March 2014 January 2014 December 2013 November 2013 October 2013 September 2013 August 2013 July 2013 June 2013 May 2013 April 2013 March 2013 February 2013 January 2013 December 2012 November 2012 October 2012

    Original URL path: http://www.dwscientific.co.uk/blog/whitley-colour-touchscreens/ (2016-02-11)
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  • Tag Archive for "Colour Touchscreens" -
    by Alex Rhodes Categories Anaerobic Australia Germany Hypoxystations News Press Releases No Comments Tags Anaerobic Workstation Colour Touchscreens Don Whitley Scientific hypoxic workstation Don Whitley A and H Workstations now feature modern easy to use colour touch screen interfaces These colour touchscreens replace the gauges dials and switches of workstations of the past and are a fitting match for the advanced scientific instruments that Don Whitley Scientific provide All options and settings you would expect to access on your Don Whitley workstation feature on these unique clear displays Set password protected user levels to control what can be done and by whom on the workstation Complete a range of functions such as O2 calibration and humidity Control mains power internal lights and set audible alarms A generous screen size of 7 making controlled parameters easily visible Download temperature humidity and chamber pressure data in seconds via USB Unique to Don Whitley workstations Tweet Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014 August 2014 July 2014 June 2014 May 2014 April 2014 March 2014 January 2014 December 2013 November 2013 October 2013 September 2013 August 2013 July 2013 June 2013 May 2013 April 2013 March 2013 February 2013 January 2013 December 2012 November 2012 October 2012 September 2012 August 2012 July 2012 June

    Original URL path: http://www.dwscientific.co.uk/blog/tag/colour-touchscreens/ (2016-02-11)
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  • H135: Taller, Deeper, Wider.
    such as live cell imaging devices microscopes plate readers etc Be sure to discuss your requirements with us at the earliest opportunity The generous internal height also facilitates easy pipetting All cell manipulations can be performed without removing them from your required hypoxic conditions With a volume twice that of a H35 Hypoxystation the H135 also comes fitted with a large removable front available with either two or three ports plus the same great features and benefits as other Whitley Workstations including Rapid 12 litre airlock H135 Hypoxystation Three gas operation The Whitley Internal HEPA Filtration System with Enhanced Biological Containment The option of being connected to a Whitley i2 Instrument Workstation 7 full colour touch screen that is Ethernet enabled for remote access Internal dimensions w x d x h are 1100mm 43 3 x 750mm 29 5 x 710mm 28 External dimensions w x d x h are 1452mm 57 25 x 1056mm 41 5 x 993mm 39 Representatives from Don Whitley Scientific will be attending the Keystone Symposia in Dublin 12 17 May where you can be one of the first to see this revolutionary product Watch the introductory video here Leave a Reply Click here to cancel reply You must be logged in to post a comment Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December

    Original URL path: http://www.dwscientific.co.uk/blog/h135-taller-deeper-wider/ (2016-02-11)
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  • Tag Archive for "H135" -
    and can accommodate a variety of items of equipment such as live cell imaging devices microscopes plate readers etc Be sure to discuss your requirements with us at the earliest opportunity The generous internal height also facilitates easy pipetting All cell manipulations can be performed without removing them from your required hypoxic conditions With a volume twice that of a H35 Hypoxystation the H135 also comes fitted with a large removable front available with either two or three ports plus the same great features and benefits as other Whitley Workstations including Rapid 12 litre airlock H135 Hypoxystation Three gas operation The Whitley Internal HEPA Filtration System with Enhanced Biological Containment The option of being connected to a Whitley i2 Instrument Workstation 7 full colour touch screen that is Ethernet enabled for remote access Internal dimensions w x d x h are 1100mm 43 3 x 750mm 29 5 x 710mm 28 External dimensions w x d x h are 1452mm 57 25 x 1056mm 41 5 x 993mm 39 Representatives from Don Whitley Scientific will be attending the Keystone Symposia in Dublin 12 17 May where you can be one of the first to see this revolutionary product Watch the introductory video here Tweet Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014

    Original URL path: http://www.dwscientific.co.uk/blog/tag/h135/ (2016-02-11)
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  • Cell Press Webinar: Hypoxic Microenvironments
    hypoxic microenvironment triggers many of the events underlying cancer progression and stem cell maintenance and or differentiation In maintaining oxygen homeostasis oxygen levels are sensed by mitochondria communicated by reactive oxygen species ROS and conveyed by hypoxia inducible factors HIF s Hypoxia signalling pathways have far reaching consequences for cellular and tissue processes from metabolism through angiogenesis to metastasis Dr Hannele Ruohola Baker University of Washington and Dr Randall Johnson University of Cambridge will be speaking at the upcoming Cell Press webinar on Hypoxic Microenvironments which Don Whitley Scientific and HypOxygen are proud to sponsor Dr Ruohola Baker s lab investigates metabolic determinants of and miRNA function in stem cells and Dr Johnson examines the effects of hypoxia in cancer and inflammation Please join us on Thursday April 16th at 12 30 EST 18 30 GMT to hear these two internationally recognised experts on the hypoxic microenvironment speak about their work Click here to register Leave a Reply Click here to cancel reply You must be logged in to post a comment Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015 April 2015 March 2015 February 2015 January 2015 December 2014 November 2014 October 2014 September 2014 August 2014 July 2014 June 2014 May 2014 April 2014 March 2014 January 2014 December 2013 November 2013 October 2013 September 2013 August 2013 July 2013 June 2013 May 2013 April 2013

    Original URL path: http://www.dwscientific.co.uk/blog/hypoxic-microenvironments/ (2016-02-11)
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  • Hypoxia and Cancer Metabolism
    research Hypoxia signaling pathways in cancer metabolism the importance of co selecting interconnected physiological pathways Masson Ratcliffe 2014 In this paper the role of hypoxia as mediated by HIF interfacing with many different oncogenic pathways is reviewed Activated HIF both suppresses mitochondrial metabolism and up regulates biosynthesis of intermediates needed by proliferating cells in cancer Complex relationships between HIF activation and cancer phenotype are discussed in detail by these Oxford UK researchers Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth Sun Denko 2013 A new mechanism whereby activated HIF 1 affects tumor metabolism through reduced activity of the mitochondrial α ketoglutarate dehydrogenase aKGDH is described in this short paper Targeted mutagenesis of this enzyme results in cells that require exogenous lipids and citrate to grow in hypoxia inhibiting tumor growth and thus offering a novel strategy for the development of anti cancer therapeutica Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer Zecchini et al 2014 This paper explores how metabolic reprogramming from oxidative phosphorylation to aerobic glycolysis under pseudo hypoxic conditions regulated by HIF 1A is a major factor in the development of rapidly proliferating tumours Mapping of chromatin binding sites has identified a novel facilitator of this metabolic shift ARRB1 in prostate cancer the most frequent cause of death in men in North America Prolyl hydroxylase domain enzymes important regulators of cancer metabolism Yang et al 2014 Prolyl hydroxylase domain proteins PHD s act as oxygen sensors regulating the stability of HIF as part of the hypoxia response and also targeting other metabolic and biosynthetic pathways that contribute to tumor growth Yang et al review the roles of PHD enzymes in cancer metabolism including an extensive summary of PHD knockout mice and their phenotypes Metabolism addiction in pancreatic cancer Blum Kloog 2014 In this review the concept of metabolic addiction is summarized and applied to the extremely fatal pancreatic cancers Genomic aberrations accumulating during cancer cell proliferation dictate a dependency on abnormal signaling and metabolism pathways that are particularly potent in the hypoxic tumor microenvironment Impacts of HIF Ras and other signaling networks on autophagy lipid and glutamine pathways among others are reviewed as targets for cancer therapy Representatives from HypOxygen will be attending the AACR meeting in April look out for their stand to learn about the Whitley range of Hypoxystations and how they could benefit your research Leave a Reply Click here to cancel reply You must be logged in to post a comment Search the Blog Search for Search Categories Anaerobic Australia Case Study Exhibitions Germany Hypoxystations News Overseas Exhibitions Press Releases Useful Links Recent Posts Liverpool Mini Exhibition A crucial update for Dr Rob Fagan at The University of Sheffield Don Whitley Scientific visit Arab Health 2016 Hypoxic Microenvironments Cell Press Nucleus Visit HypOxygen at the AACR Meeting in San Diego Archives February 2016 January 2016 December 2015 November 2015 October 2015 September 2015 August 2015 July 2015 June 2015 May 2015

    Original URL path: http://www.dwscientific.co.uk/blog/recent-hypoxia-papers/ (2016-02-11)
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web-archive-uk.com, 2017-12-14